Kartagener's Syndrome

34 years old male patient

C/o. 1. Nasal block since childhood

2. Recurrent attacks of upper respiratory infections since childhood

3. Sterility

4. Recurrent episodes of wheezing


Patient had a broad nasal bridge with telecanthus (i.e. increased interpupillary distance)


This picture shows the patient with telecanthus (Increased interpupillary distance)

This feature (telecanthus) is common in patients who have nasal polyposis since childhood.
The presence of nasal polypi causes a splaying effect on the nasal bones causing an
increase in the interpupillary distance (telecanthus).

Both the nasal cavities of the patient was found to be filled with multiple polypi.


This picture shows the endoscopic view of nasal polypi.


X ray chest showing dextrocardia

His seminal analysis revealed azoospermia.

Clinical diagnosis: Kartagener's syndrome


Kartagener's syndrome is a symptom complex showing

1. Bilateral nasal polypi

2. Azoospermia

3. Dextrocardia

4. Situs inversus totalis (reversal of abdominal contents)

5. Bronchiectasis

This disease has an autosomal recessive mode of inheritance. The primary defect lies in the
ciliary mechanism of the body. The cilia present in the body (in the nose, lungs, sperms) do not
beat normally leading to this defect.

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